Neurodegenerative disease

Complement mediates pathological pruning

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    Hong, S. et al. Complement and microglia mediate early synapse loss in Alzheimer mouse models. Science http://dx.doi.org/10.1126/science.aad8373 (2016)

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Heppner, F.L. et al. Immune attack: the role of inflammation in Alzheimer disease. Nat. Rev. Neurosci. 16, 358–372 (2015)

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Whalley, K. Complement mediates pathological pruning. Nat Rev Neurosci 17, 336 (2016) doi:10.1038/nrn.2016.52

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