Abstract
The genomes described this month reflect the overall historical bias of microbial genomics towards pathogenic bacteria. Although the balance is now being redressed to some extent, especially through the study of extremophiles, it is still the case that the opportunities provided by genomic studies are primarily taken up by those who study bacterial pathogenicity. This part of the field is, however, being broadened by including the study of pathogens of animals, insects and plants alongside those that afflict humans.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Cerdeño-Tárraga, A. M. et al. The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129. Nucleic Acids Res. (doi: 10.1093/nar/gkg874).
Daubin, V. & Perriere, G. G+C3 structuring along the genome: a common feature in prokaryotes. Mol. Biol. Evol. 20, 471–483 (2003).
Bentley, S.D. et al. Sequencing and analysis of the genome of the Whipple's disease bacterium Tropheryma whipplei. Lancet 361, 637–644 (2003).
Raoult, D. et al. Tropheryma whipplei Twist: a human pathogenic Actinobacteria with a reduced genome. Genome Res. 13, 1800–1809 (2003).
Renesto, P. et al. Genome-based design of a cell-free culture medium for Tropheryma whipplei. Lancet 362, 447–449 (2003).
Duchaud, E. et al. The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens. Nat. Biotechnol. doi:10.1038/nbt886 (2003).
Parkhill, J. et al. Genome sequence of Yersinia pestis, the causative agent of plague. Nature 413, 523–527 (2001).
Baar, C. et al. Complete genome sequence and analysis of Wolinella succinogenes. Proc. Natl Acad. Sci. USA 100, 11690–11695 (2003).
Parkhill, J. et al. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences. Nature 403, 665–668 (2000).
Alm, R.A. et al. Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori. Nature 397, 176–180 (1999).
Tomb, J.F. et al. The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 388, 539–547 (1997).
Fredricks, D.N. & Relman, D.A. Localization of Tropheryma whippelii rRNA in tissues from patients with Whipple's disease. J. Infect. Dis. 183, 1229–1237 (2001).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Crossman, L., Cerdeño-Tárraga, A., Bentley, S. et al. Pathogenomics. Nat Rev Microbiol 1, 176–177 (2003). https://doi.org/10.1038/nrmicro778
Issue Date:
DOI: https://doi.org/10.1038/nrmicro778