Genome Watch | Published:

Found in translation

Nature Reviews Microbiology volume 12, page 238 (2014) | Download Citation

This month's Genome Watch highlights a recent study that used high-throughput sequencing to identify the mRNAs that are actively translated during the life cycle of a protozoan parasite.

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References

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    et al. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science 324, 218–223 (2009).

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    et al. Comparative ribosome profiling reveals extensive translational complexity in different Trypanosoma brucei life cycle stages. Nucl. Acids Res. (2014).

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    et al. Regulation of Trypanosoma brucei total and polysomal mRNA during development within its mammalian host. PLoS ONE 8, e67069 (2013).

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    & Changes in polysome profiles accompany trypanosome development. Mol. Biochem. Parasitol. 97, 189–198 (1998).

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    & Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei. Mol. Biochem. Parasitol. 161, 76–79 (2008).

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Author information

Affiliations

  1. Lia Chappell is at the Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

    • Lia Chappell

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Competing interests

The author declares no competing financial interests.

Corresponding author

Correspondence to Lia Chappell.

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DOI

https://doi.org/10.1038/nrmicro3243

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