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Brothers in arms


This month we discuss the insights that genomics can provide into the evolution and speciation of virulent human pathogens, using two pertinent examples from the Yersinia and Burkholderia genera.

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Figure 1: World distribution of plague, 1998.
Figure 2: Actin tail formation by Burkholderia pseudomallei.


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Burkholderia mallei

Burkholderia pseudomallei

Y. pestis strain CO92

Y. pestis strain 91001

Y. pestis KIM 10 strain

Y. pseudotuberculosis strain IP32953


The Pathogen Sequencing Unit

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Thomson, N., Holden, M. & Parkhill, J. Brothers in arms. Nat Rev Microbiol 3, 100–101 (2005).

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