The incidence of many diseases rises sharply with age. Although clearly separable, ageing and certain age-related diseases might share common mechanisms. Cellular metabolism and subsequent generation of reactive oxygen species might contribute both to the rate at which we age and to our susceptibility to numerous chronic diseases, therefore therapies that directly target the ageing process might provide new ways to treat human diseases.
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I am grateful to members of my laboratory for useful suggestions, in particular, to I. Rovira for help with this manuscript. This work was supported by intramural National Institutes of Health funding.
The author declares no competing financial interests.
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Finkel, T. Radical medicine: treating ageing to cure disease. Nat Rev Mol Cell Biol 6, 971–976 (2005). https://doi.org/10.1038/nrm1763
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