●Keeping cartographers busy. Hayden, M. S. & Ghosh, S. Nature Cell Biology February (2004) Understanding protein network topology — how proteins of a particular pathway interact with each other — is the next step in signalling biology. This News and Views article discusses a proteomic approach to tackle this problem.

●Passenger acrobatics. Higuchi, T. & Uhlmann, F. Nature 18/25 December (2003) Chromosomal passenger proteins make up the aurora-B kinase complex, which shows marked changes in localization during mitosis. How and why these changes occur are discussed in this News and Views article.

●Role of the cytoskeleton during leukocyte responses. Vicente-Manzanares, M. & Sánchez-Madrid, F. Nature Reviews Immunology February (2004)

●Presynaptic ionotropic receptors and the control of transmitter release. Engelman, H. S. & MacDermott, A. B. Nature Reviews Neuroscience February (2004)

●Using human neural stem cells to model neurological disease. Jakel, R. J., Schneider, B. L. & Svendsen, C. N. Nature Reviews Genetics February (2004)

●Myelin inhibitors: does NO mean GO? Raisman, G. Nature Reviews Neuroscience February (2004)

●Nuclear transport and cancer: from mechanism to intervention. Kau, T. K., Way, J. C. & Silver, P. A. Nature Reviews Cancer February (2004)

●Shape-shifting protein channel. Benach, J. & Hunt, J. F. Nature 1 January (2004) This News and Views article reports on the recent crystallization of the protein channel, or translocase, that allows newly made proteins to move across cellular membranes.

●The SWI/SNF complex — chromatin and cancer. Roberts, C. W. M. & Orkin, S. H. Nature Reviews Cancer February (2004)

●Virus entry: molecular mechanisms and biomedical applications. Dimitrov, D. S. Nature Reviews Microbiology February (2004)

●Cytokine–receptor pairing: accelerating discovery of cytokine function. Foster, D., Parrish-Novak, J., Fox, B. & Xu, W. Nature Reviews Drug Discovery February (2004)

●Network biology: understanding the cell's functional organization. Barabási, A.-L. & Oltvai, Z. N. Nature Reviews Genetics February (2004)