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The future of CRISPR technologies in agriculture

Nature Reviews Molecular Cell Biology volume 19, pages 275276 (2018) | Download Citation

Conventional plant breeding is unlikely to meet increasing food demands and other environmental challenges. By contrast, CRISPR technology is erasing barriers to genome editing and could revolutionize plant breeding. However, to fully benefit from the CRISPR revolution, we should focus on resolving its technical and regulatory uncertainties.

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References

  1. 1.

    et al. A programmable dual-RNA–guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816–821 (2012).

  2. 2.

    et al. Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system. Cell 163, 759–771 (2015).

  3. 3.

    , & Progress and prospects in plant genome editing. Nat. Plants 3, 17107 (2017).

  4. 4.

    , , , & Engineering quantitative trait variation for crop improvement by genome editing. Cell 171, 470–480 (2017).

  5. 5.

    et al. Programmable base editing of A·T to G·C in genomic DNA without DNA cleavage. Nature 551, 464–471 (2017).

Download references

Acknowledgements

The author is supported by grants from the National Natural Science Foundation of China (31788103) and the National Key Research and Development Program of China (2016YFD0101804).

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Affiliations

  1. State Key Laboratory of Plant Cell and Chromosome Engineering and Center for Genome Editing, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.

    • Caixia Gao

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The author declares no competing financial interests.

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Correspondence to Caixia Gao.

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DOI

https://doi.org/10.1038/nrm.2018.2

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