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Nuclear reprogramming and cell replacement therapies

Nature Reviews Molecular Cell Biology volume 17, pages 137–138 (2016)Cite this article

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Abstract

This issue of Nature Reviews Molecular Cell Biology celebrates the 10th anniversary of the pioneering 2006 publication reporting the derivation of induced pluripotent stem cells. Earlier work that led in this direction included nuclear transfer experiments in Amphibia and then in mammals (including humans), followed by the derivation of embryonic stem cells and the identification of cell type-determining transcription factors. Cell replacement therapy for certain human disorders may soon be available. However, a major threat to progress is from regulatory bodies intimidated by compensatory legal judgments.

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  1. The Gurdon Institute, University of Cambridge, Tennis Court Road, CB2 1QN, Cambridge, UK

    J. B. Gurdon

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  1. J. B. Gurdon
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Correspondence to J. B. Gurdon.

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Gurdon, J. Nuclear reprogramming and cell replacement therapies. Nat Rev Mol Cell Biol 17, 137–138 (2016). https://doi.org/10.1038/nrm.2016.11

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