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Neuroimmunology in 2017: The central nervous system: privileged by immune connections

Nature Reviews Immunology volume 18, pages 8384 (2018) | Download Citation


Over the past few years, interest in the field of neuroimmunology has expanded dramatically, thanks largely to new technologies that have advanced our understanding of the intimate connections between the nervous and immune systems1. Here, we highlight key advances in 2017 that have defined new roles for microglia in brain maintenance, for cytokines as neuromodulators and for the immune system in peripheral nerve activity.

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The authors thank A. Impagliazzo for help with the figure.

Author information


  1. Jonathan Kipnis is at the Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia 22908, USA.

    • Jonathan Kipnis
  2. Anthony J. Filiano is at the Robertson Clinical and Translational Cell Therapy Program and the Department of Neurosurgery, Duke University, Durham, North Carolina 27710, USA.

    • Anthony J. Filiano


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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Jonathan Kipnis.

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