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Immunometabolism in 2017

Driving immunity: all roads lead to metabolism

Nature Reviews Immunology volume 18, pages 81–82 (2018)Cite this article

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In 2017, studies of cellular metabolism broadly permeated immunological research. Accumulating data support the view that understanding how metabolism regulates immune cell function could provide new therapeutic opportunities for the many diseases associated with immune system dysregulation.

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Figure 1: Metabolic programmes regulate immune cell function.

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Acknowledgements

The authors are supported by grants from the National Institutes of Health (to E.J.P. and E.L.P.), the Deutsche Forschungsgemeinschaft (to E.J.P.) and the Max Planck Society (to E.J.P. and E.L.P.).

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Authors and Affiliations

  1. Edward J. Pearce is at the Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany; and at the Faculty of Biology, University of Freiburg, Freiburg, Germany.,

    Edward J. Pearce

  2. and at the Faculty of Biology, University of Freiburg, Freiburg, Germany.,

    Edward J. Pearce

  3. Erika L. Pearce is at the Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.,

    Erika L. Pearce

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  1. Edward J. Pearce
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Correspondence to Edward J. Pearce or Erika L. Pearce.

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Competing interests

E.J.P. and E.L.P. consult with Third Rock Ventures on the research area covered by this commentary.

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Pearce, E., Pearce, E. Driving immunity: all roads lead to metabolism. Nat Rev Immunol 18, 81–82 (2018). https://doi.org/10.1038/nri.2017.139

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