NAFLD in 2017

Novel insights into mechanisms of disease progression

In 2017, there have been substantial advances in our understanding of the immunological and endocrine mechanisms of disease progression in NAFLD, paving the way for novel therapeutic strategies.

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Figure 1: NAFLD pathogenesis.

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Correspondence to Philip N. Newsome.

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Competing interests

P.N.N. has served as a speaker, a consultant and an advisory board member for AbbVie, Boehringer Ingelheim, Gilead, Intercept, Janssen, Novartis, Novo Nordisk, Pharmaxis and Shire, and has received research funding from these organizations on behalf of the University of Birmingham, UK. R.S.K. has received research funding from the National Institute of Health Research.

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Khan, R., Newsome, P. Novel insights into mechanisms of disease progression. Nat Rev Gastroenterol Hepatol 15, 71–72 (2018). https://doi.org/10.1038/nrgastro.2017.181

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