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Vitamin D and IBD: moving towards clinical trials

A new study reports that low vitamin D levels are associated with increased morbidity and severity of IBD. A number of issues must now be addressed to enable the optimal design of interventional studies to test whether vitamin D supplementation can improve outcomes in this disease.

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Figure 1: Vitamin D maintains gastrointestinal homeostasis.


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Work in the Cantorna laboratory was supported by the NIH/National Institute of Neurological Disorders and Stroke NS067563 and National Center for Complementary and Alternative Medicine and the Office of Dietary Supplements AT005378.

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Correspondence to Margherita T. Cantorna.

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The author declares no competing financial interests.

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Cantorna, M. Vitamin D and IBD: moving towards clinical trials. Nat Rev Gastroenterol Hepatol 13, 322–323 (2016).

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