Liver transplantation

Evading antigens—ABO-incompatible liver transplantation

Whereas the status of the liver as privileged and exempt from humoral rejection has fallen, attempts at breaching the blood group barrier during transplantation have continued. Previously restricted to paediatric patients and emergencies, advances in immunosuppression protocols have improved outcomes to the point that ABO-incompatible liver transplantation might be more widely used in adults.

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Correspondence to Ronald W. Busuttil.

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Zarrinpar, A., Busuttil, R. Evading antigens—ABO-incompatible liver transplantation. Nat Rev Gastroenterol Hepatol 12, 676–678 (2015). https://doi.org/10.1038/nrgastro.2015.193

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