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Coeliac disease

Missing villi? The search for coeliac disease in the Asia–Pacific region

Epidemiology studies have shown an 1% prevalence of coeliac disease in Europe, North America, the Middle East and South America, but the prevalence in the Asia–Pacific region remains relatively unknown. Now, Makharia et al. have proposed much needed recommendations to help tackle the problem of coeliac disease in this region.

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Figure 1: Prevalence of coeliac disease in the Asia–Pacific region.

References

  1. Fasano, A. et al. Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study. Arch. Intern. Med. 163, 286–292 (2003).

    Article  Google Scholar 

  2. Mustalahti, K. et al. The prevalence of celiac disease in Europe: results of a centralized, international mass screening project. Ann. Med. 42, 587–595 (2010).

    Article  Google Scholar 

  3. Alarida, K. et al. Coeliac disease in Libyan children: a screening study based on the rapid determination of anti-transglutaminase antibodies. Dig. Liver Dis. 43, 688–691 (2011).

    Article  CAS  Google Scholar 

  4. Dalgic, B. et al. Prevalence of celiac disease in healthy Turkish school children. Am. J. Gastroenterol. 106, 1512–1517 (2011).

    Article  CAS  Google Scholar 

  5. Cummins, A. G. & Roberts-Thomson, I. C. Prevalence of celiac disease in the Asia–Pacific region. J. Gastroenterol. Hepatol. 24, 1347–1351 (2009).

    Article  Google Scholar 

  6. Makharia, G. K. et al. Prevalence of celiac disease in the northern part of India: a community based study. J. Gastroenterol. Hepatol. 26, 894–900 (2011).

    Article  Google Scholar 

  7. Makharia, G. K. et al. Issues associated with the emergence of coeliac disease in the Asia–Pacific region: a working party report of the World Gastroenterology Organization and the Asian Pacific Association of Gastroenterology. J. Gastroenterol. Hepatol. http://dx.doi.org/10.1111/jgh.12514.

  8. Ganesh, R., Suresh, N. & Sathiyasekaran, M. Celiac disease, still an uncommon problem in Tamilians? Indian J. Gastroenterol. 28, 189 (2009).

    Article  CAS  Google Scholar 

  9. Karell, K. et al. HLA types in celiac disease patients not carrying the DQA1 *05-DQB1 *02 (DQ2) heterodimer: results from the European Genetics Cluster on Celiac Disease. Hum. Immunol. 64, 469–477 (2003).

    Article  CAS  Google Scholar 

  10. Arshad, H. & Ahmad, Z. Histologic findings in biopsies/resection specimens from the small intestine with special emphasis on celiac disease: experience from a developing country in South Asia. Ann. Diagn. Pathol. 16, 436–440 (2012).

    Article  Google Scholar 

Download references

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Correspondence to Ciarán P. Kelly.

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Competing interests

C.P.K. is a scientific advisor and shareholder in Alvine Pharmaceuticals and ImmunosanT and a scientific advisor for Alba Therapeutics. T.G.T. declares no competing interests.

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Theethira, T., Kelly, C. Missing villi? The search for coeliac disease in the Asia–Pacific region. Nat Rev Gastroenterol Hepatol 11, 204–205 (2014). https://doi.org/10.1038/nrgastro.2014.26

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