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Hepatitis B in 2014

HBV research moves forward—receptors and reactivation

Since the discovery of HBV in the 1960s, its life cycle and the natural history of infection have been delineated by many studies. In 2014, new findings concerning the host–virus interaction and new studies of HBV reactivation from occult HBV infection are of considerable interest.

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Figure 1: Potential therapeutic means to inhibit HBV entry into hepatocytes.


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Correspondence to Man-Fung Yuen.

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M.-F.Y. is member of advisory boards and/or speaker's bureau for Abbvie, Bristol–Myers Squibb, Gilead, GlaxoSmithKline, Janssen Pharmaceutica and Roche Diagnostics. L.-C.L. is a member of advisory boards and/or speaker's bureau for Arrowhead Research, Bristol–Myers Squibb and Gilead.

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Yuen, MF., Lai, CL. HBV research moves forward—receptors and reactivation. Nat Rev Gastroenterol Hepatol 12, 70–72 (2015).

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