Faecal microbiota transplantation (FMT) is an effective treatment for Clostridium difficile infection, but concern exists over its safety in immunocompromised patients. A multicentre, retrospective analysis of 80 patients who received FMT found that no patient contracted an infection definitively related to treatment, and an overall cure rate of 89% was reported. The researchers conclude that FMT is a safe treatment option for this subgroup of patients.