Faecal microbiota transplantation (FMT) is an effective treatment for Clostridium difficile infection, but concern exists over its safety in immunocompromised patients. A multicentre, retrospective analysis of 80 patients who received FMT found that no patient contracted an infection definitively related to treatment, and an overall cure rate of 89% was reported. The researchers conclude that FMT is a safe treatment option for this subgroup of patients.
References
Kelly, C. R. et al. Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompromised patients. Am. J. Gastroenterol. 10.1038/ajg.2014.133
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FMT: a safe treatment for Clostridium difficile infection in immunocompromised patients. Nat Rev Gastroenterol Hepatol 11, 454 (2014). https://doi.org/10.1038/nrgastro.2014.112
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DOI: https://doi.org/10.1038/nrgastro.2014.112