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Structural changes in functional gastrointestinal disorders

Functional gastrointestinal disorders (FGIDs) have traditionally been diagnosed on the basis of characteristic symptom patterns in the absence of organic disease that explains the symptoms. Evidence is now emerging that structural abnormalities in the brain might have a role in the pathophysiology of FGIDs.

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Correspondence to Emeran A. Mayer.

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The authors declare no competing financial interests.

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Mayer, E., Tillisch, K. & Ellingson, B. Structural changes in functional gastrointestinal disorders. Nat Rev Gastroenterol Hepatol 10, 200–202 (2013).

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