In their meta-analysis, Wanders et al. determined the sensitivity, specificity and real-time negative predictive value of endoscopic imaging techniques for the diagnosis of non-neoplastic versus neoplastic colonic lesions. They conclude that narrow-band imaging, image-enhanced endoscopy, Fuji intelligent chromoendoscopy and confocal laser endomicroscopy can all be used to make a reliable diagnosis, but not autofluoresence imaging.