Conservative treatment of high-output postoperative pancreatic fistulas (POPFs) includes prolonged fasting with nutritional support. However, the choice between enteral and parenteral nutrition is arbitrary. A randomized clinical trial that compared these two types of nutritional support has demonstrated that enteral feeding is associated with a substantially higher closure rate and a shorter time to closure of POPFs.
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Bassi, C., Malleo, G. Postoperative pancreatic fistula: use of enteral nutrition. Nat Rev Gastroenterol Hepatol 8, 427–428 (2011). https://doi.org/10.1038/nrgastro.2011.113
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DOI: https://doi.org/10.1038/nrgastro.2011.113
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