Confocal laser endomicroscopy (CLE) is an emerging technology with important applications in gastrointestinal imaging. Fluorescein, the contrast agent most commonly employed in CLE, has not yet been approved by the FDA for intravenous use with this technique in the gastrointestinal setting. A cross-sectional study suggests that fluorescein is generally safe and usually has none or only mild adverse effects in patients undergoing CLE.
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Paramsothy, S., Leong, R. Fluorescein contrast in confocal laser endomicroscopy. Nat Rev Gastroenterol Hepatol 7, 366–368 (2010). https://doi.org/10.1038/nrgastro.2010.83
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DOI: https://doi.org/10.1038/nrgastro.2010.83
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