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Hepatitis

Hepatitis E vaccination—is HEV 239 the breakthrough?

Nature Reviews Gastroenterology & Hepatology volume 8, pages 8–10 (2011)Cite this article

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No approved vaccine is currently available against hepatitis E virus (HEV), which can cause acute hepatitis E. A large-scale phase III study involving more than 100,000 Chinese adults has reported that the recombinant HEV vaccine, HEV 239, prevented acute hepatitis E with a vaccine efficacy of 94–100%.

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Acknowledgements

This work was supported by a grant from the German Federal Ministry of Education and Research (01EO0802).

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  1. Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Carl-Neuberg Strasse 1, Hannover, 30625, Germany

    Heiner Wedemeyer & Sven Pischke

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  1. Heiner Wedemeyer
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  2. Sven Pischke
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Correspondence to Heiner Wedemeyer.

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The authors declare no competing financial interests.

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Wedemeyer, H., Pischke, S. Hepatitis E vaccination—is HEV 239 the breakthrough?. Nat Rev Gastroenterol Hepatol 8, 8–10 (2011). https://doi.org/10.1038/nrgastro.2010.207

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