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An ecosystem of cancer cell line factories to support a cancer dependency map

Nature Reviews Genetics volume 16, pages 373374 (2015) | Download Citation


Jesse Boehm and Todd Golub call for an international effort to establish >10,000 cancer cell line models as a community resource. Cancer cell line factories will facilitate the creation of a cancer dependency map, connecting cancer genomics to therapeutic dependencies.

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Author information


  1. Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, Massachusetts 02142, USA.

    • Jesse S. Boehm
    •  & Todd R. Golub
  2. Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.

    • Todd R. Golub
  3. Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115, USA.

    • Todd R. Golub
  4. Howard Hughes Medical Institute, 4000 Jones Bridge Road, Chevy Chase, Maryland 20815, USA.

    • Todd R. Golub


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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Jesse S. Boehm.

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