The big medical data miss: challenges in establishing an open medical resource


I call for an international open medical resource to provide a database for every individual's genomic, metabolomic, microbiomic, epigenomic and clinical information. This resource is needed in order to facilitate genetic diagnoses and transform medical care.

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  1. 1

    Becklund, L. As I lay dying. Los Angeles Times [online], (2015).

    Google Scholar 

  2. 2

    Ten Breakthrough Technologies 2015. MIT Technology Review [online], (2015).

  3. 3

    Topol, E. J. Individualized medicine from prewomb to tomb. Cell 157, 241–253 (2014).

    CAS  Article  Google Scholar 

  4. 4

    Topol, E. J. The Patient Will See You Now (Basic Books, 2015).

    Google Scholar 

  5. 5

    Topol, E. J., Steinhubl, S. R. & Torkamani, A. Digital medical tools and sensors. JAMA 313, 353–354 (2015).

    CAS  Article  Google Scholar 

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Correspondence to Eric J. Topol.

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Competing interests

The author is Advisor to Illumina, Genapsys, Google and Edico Genome, and Co-Founder of Cypher Genomics.

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Topol, E. The big medical data miss: challenges in establishing an open medical resource. Nat Rev Genet 16, 253–254 (2015).

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