The artificial pancreas in 2017

The year of transition from research to clinical practice

The artificial pancreas — the automated closed-loop control of diabetes mellitus — made its first outpatient strides in 2011. In 2017, the results of long-term clinical trials on the artificial pancreas were published, the first hybrid commercial artificial pancreas system was approved and the artificial pancreas was tested under increasingly demanding conditions. Thus, artificial pancreas technology is here to stay.

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Figure 1: Embedded and mobile artificial pancreas system configurations.

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Acknowledgements

The author's work on closed-loop control is supported by the National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases grants DP3 DK101055, RO1 DK 085623 and UC4 108483 – the International Diabetes Closed-Loop Trial, and by the University of Virginia's Strategic Investment in Type 1 Diabetes.

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Correspondence to Boris Kovatchev.

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B.K. has received speaking engagements/honoraria from Dexcom and Sanofi; research support managed by the University of Virginia from Ascensia Diabetes Care, Dexcom, Roche Diagnostics and Tandem Diabetes Care; patent royalties managed by the University of Virginia from Johnson & Johnson and Sanofi; and is shareholder/board member of TypeZero Technologies, Inc.

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Kovatchev, B. The year of transition from research to clinical practice. Nat Rev Endocrinol 14, 74–76 (2018). https://doi.org/10.1038/nrendo.2017.170

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