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Islet-cell biology in 2015

Understanding secretion, ageing and death in β cells

Nature Reviews Endocrinology volume 12, pages 72–74 (2016)Cite this article

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The pancreatic islets of Langerhans have been intensively investigated for many years, largely because of their central role in the pathogenesis of type 1 and type 2 diabetes mellitus. Notable advances in 2015 related to glucose-stimulated insulin secretion in β cells, β-cell death and the role of epigenetics in β-cell heterogeneity.

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References

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Authors and Affiliations

  1. Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, One Joslin Place, Boston, 02215, Massachusetts, USA

    Gordon C. Weir

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  1. Gordon C. Weir
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Correspondence to Gordon C. Weir.

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Weir, G. Understanding secretion, ageing and death in β cells. Nat Rev Endocrinol 12, 72–74 (2016). https://doi.org/10.1038/nrendo.2015.236

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