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Neuroendocrine cancer

Closing the GAPP on predicting metastases

A promising grading system to predict metastasis in patients with phaeochromocytoma and paraganglioma assigns risk according to selected histological and other criteria. Such risk stratification might be useful for personalized management and screening programmes, as it could limit the costs of follow-up and reduce the risk of disseminated disease.

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Acknowledgements

The authors would like to acknowledge the support of Deutsche Forschungsgemeinschaft EI855/1/1, European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement 259735 (ENS@T-Cancer).

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Correspondence to Graeme Eisenhofer.

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Eisenhofer, G., Tischler, A. Closing the GAPP on predicting metastases. Nat Rev Endocrinol 10, 315–316 (2014). https://doi.org/10.1038/nrendo.2014.41

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