Adiponectin and fibroblast growth factor 21 (FGF21) regulate glucose and lipid metabolism in similar ways and are both critically involved in the antidiabetic effects of thiazolidinedione drugs. Studies in mice now shed light on how adiponectin and FGF21 are functionally linked, which has intriguing implications for the therapeutic potential of these hormones.
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Goetz, R. Adiponectin—a mediator of specific metabolic actions of FGF21. Nat Rev Endocrinol 9, 506–508 (2013). https://doi.org/10.1038/nrendo.2013.146
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DOI: https://doi.org/10.1038/nrendo.2013.146
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