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Pharmacotherapy

Hypothyroidism—should levothyroxine be taken at bedtime?

Nature Reviews Endocrinology volume 7, pages 195–196 (2011)Cite this article

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Up to one-third of patients treated with levothyroxine for primary hypothyroidism have biochemical evidence of inadequate thyroid hormone replacement. Could treatment effects of levothyoxine be optimized by bedtime administration on an empty stomach? A new study reveals the answer and also sheds light on other possible benefits of this alternative timing.

“...bedtime rather than morning administration of levothyroxine improves thyroid hormone levels...”

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  1. Department of Endocrinology, Royal Free Hampstead NHS Trust, Pond Street, NW3 2QG, London, UK

    Mark Vanderpump

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  1. Mark Vanderpump
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The author declares no competing financial interests.

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Vanderpump, M. Hypothyroidism—should levothyroxine be taken at bedtime?. Nat Rev Endocrinol 7, 195–196 (2011). https://doi.org/10.1038/nrendo.2011.29

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  • DOI: https://doi.org/10.1038/nrendo.2011.29

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