PrimeView | Published:

Sickle cell disease

Nature Reviews Disease Primers volume 4, Article number: 18011 (2018) | Download Citation

This PrimeView is an illustrated summary of the Primer for sickle cell disease. Download the PDF for an accessible version

PrimeViews are illustrated summaries of Primers. In order to access the high resolution version of this PrimeView please login, or select one of the purchase options below.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

This PrimeView highlights the complex pathophysiological mechanisms of sickle cell disease (SCD), which stem from the polymerization of sickle haemoglobin (HbS), a mutant haemoglobin variant. Erythrocytes containing HbS polymers assume the crescent shape that gives SCD its name.

About this article

Publication history