The symptoms of amyotrophic lateral sclerosis (ALS) include signs of upper motor neuron and lower motor neuron dysfunction. These symptoms, and the diagnostic work-up for ALS, are the main focus of this PrimeView, which accompanies the Primer by Hardiman and colleagues.
About this article
Cite this article
Amyotrophic lateral sclerosis. Nat Rev Dis Primers 3, 17072 (2017). https://doi.org/10.1038/nrdp.2017.72