Amyotrophic lateral sclerosis

The symptoms of amyotrophic lateral sclerosis (ALS) include signs of upper motor neuron and lower motor neuron dysfunction. These symptoms, and the diagnostic work-up for ALS, are the main focus of this PrimeView, which accompanies the Primer by Hardiman and colleagues.

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Amyotrophic lateral sclerosis. Nat Rev Dis Primers 3, 17072 (2017). https://doi.org/10.1038/nrdp.2017.72

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