The availability of animal models of pemphigus has enabled researchers to understand the pathological mechanisms of this autoimmune disease. This PrimeView illustrates how autoantibodies against proteins that are involved in cell adhesion can lead to the formation of blisters and erosions, the hallmark lesions of pemphigus.
About this article
Cite this article
Pemphigus. Nat Rev Dis Primers 3, 17027 (2017). https://doi.org/10.1038/nrdp.2017.27