This PrimeView highlights the pathophysiology of acute-on-chronic liver failure in cirrhosis. In patients with cirrhosis, triggers of inflammation, such as sepsis and alcoholic hepatitis, can cause acute liver decompensation and organ failure, resulting in high short-term mortality.
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Acute-on-chronic liver failure in cirrhosis. Nat Rev Dis Primers 2, 16042 (2016). https://doi.org/10.1038/nrdp.2016.42