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Patent foramen ovale

Patent foramen ovale (PFO) is the consequence of failed closure of the foramen ovale, a normal structure that is present in the fetus to direct blood flow directly from the right to the left atrium, bypassing the pulmonary circulation.

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Patent foramen ovale. Nat Rev Dis Primers 2, 15087 (2016). https://doi.org/10.1038/nrdp.2015.87

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