Menopause is the age-related (primary) or iatrogenic (secondary) loss of female reproductive function. Menopausal women are at increased risk for many conditions including cardiovascular disease, osteoporosis and some cancers, by mechanisms that are not yet fully understood.
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Menopause. Nat Rev Dis Primers 1, 15054 (2015). https://doi.org/10.1038/nrdp.2015.54