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Industry–academia collaborations for biomarkers

Abstract

Several types of collaboration are being pursued to identify, validate and apply new biomarkers. Here, we highlight examples of such initiatives and discuss the challenges, approaches to address these challenges and key factors for success.

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References

  1. Wholley, D. The Biomarkers Consortium. Nat. Rev. Drug. Discov. 13, 791–792 (2014).

    Article  CAS  PubMed  Google Scholar 

  2. Stephenson, D. & Sauer, J. M. The Predictive Safety Testing Consortium and the Coalition Against Major Diseases. Nat. Rev. Drug. Discov. 13, 793–794 (2014).

    Article  CAS  PubMed  Google Scholar 

  3. Lessl, M. et al. Crowd sourcing in drug discovery. Nat. Rev. Drug. Discov. 10, 241–242 (2011).

    Article  CAS  PubMed  Google Scholar 

  4. Küffner, R. et al. Crowdsourced analysis of clinical trial data to predict amyotrophic lateral sclerosis progression. Nat. Biotech. 33, 51–57 (2015).

    Article  Google Scholar 

  5. Dorsch, H. et al. Grants4Targets — an open innovation initiative to foster drug discovery collaborations between academia and the pharmaceutical industry. Nat. Rev. Drug. Discov. 14, 74–76 (2015).

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

The authors would like to thank T. Schlange, M. Lessl, H. Dorsch (all at Bayer, Germany), and H.-D. Volk (at the Berlin-Brandenburg Center for Regenerative Therapies, Charité, Berlin, Germany) for helpful discussions, and P. Carrigan for critical reading of the manuscript.

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Correspondence to Khusru Asadullah.

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L.L. and P.R. have no conflict of interest to declare. K.A., A.B. and M.G. are employees and shareholders of Bayer.

Supplementary information

Supplementary information S1 (table)

Examples of biomarker consortia supported by public funding in Europe and the United States (PDF 92 kb)

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Asadullah, K., Busch, A., Gottwald, M. et al. Industry–academia collaborations for biomarkers. Nat Rev Drug Discov 14, 805–806 (2015). https://doi.org/10.1038/nrd4727

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