Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Beyond magic bullets: true innovation in health care


The time has come to move beyond product-focused 'magic bullet' therapeutic development strategies towards models that can also incorporate devices, tools and services to provide integrated health-care solutions.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. World Economic Forum. The Global Economic Burden of Non-communicable Diseases (Harvard School of Public Health, 2011).

  2. Schadt, E. E. & Björkegren, J. L. NEW: network-enabled wisdom in biology, medicine, and health care. Sci. Transl. Med. 4, 115rv1 (2012).

    Article  PubMed  Google Scholar 

  3. Kane, J. M. Improving treatment adherence in patients with schizophrenia. J. Clin. Psychiatry 72, e28 (2011).

    Article  PubMed  Google Scholar 

  4. Madan, A., Cebrian, M., Lazer, D. & Pentland, A. Social sensing for epidemiological behavior change. Proc.12th ACM Int. Conf. Ubiquitous Computing 291–300 (ACM, 2010).

    Google Scholar 

Download references


W. P. Battisti (Janssen Research & Development, USA) provided administrative and editorial support for this manuscript.

Author information

Authors and Affiliations


Corresponding author

Correspondence to Husseini K. Manji.

Ethics declarations

Competing interests

Vaibhav A. Narayan, Marco Mohwinckel, Michael Yang and Husseini K. Manji are employees of Janssen Pharmaceuticals.

Related links

Related links


Better managed care for schizophrenia patients in Germany

Recovery After an Initial Schizophrenia Episode (RAISE) initiative

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Narayan, V., Mohwinckel, M., Pisano, G. et al. Beyond magic bullets: true innovation in health care. Nat Rev Drug Discov 12, 85–86 (2013).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing