Three prevention trials in asymptomatic Alzheimer's disease patients will attempt to validate the amyloid hypothesis, evaluate biomarkers and set the stage for drug approvals.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Molecular basis for mid-region amyloid-β capture by leading Alzheimer's disease immunotherapies
Scientific Reports Open Access 16 April 2015
-
Moving beyond the pros and cons of automating cognitive testing in pathological aging and dementia: the case for equal opportunity
Alzheimer's Research & Therapy Open Access 29 August 2014
-
Performance on a pattern separation task by Alzheimer’s patients shows possible links between disrupted dentate gyrus activity and apolipoprotein E ∈4 status and cerebrospinal fluid amyloid-β42 levels
Alzheimer's Research & Therapy Open Access 15 April 2014
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Rights and permissions
About this article
Cite this article
Mullard, A. Sting of Alzheimer's failures offset by upcoming prevention trials. Nat Rev Drug Discov 11, 657–660 (2012). https://doi.org/10.1038/nrd3842
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrd3842
This article is cited by
-
Structural biology of cell surface receptors implicated in Alzheimer’s disease
Biophysical Reviews (2022)
-
Biomarkers voor de ziekte van Alzheimer: relaties met vasculaire factoren, neurodegeneratie en cognitie in de predementiële fasen
Neuropraxis (2019)
-
Molecular basis for mid-region amyloid-β capture by leading Alzheimer's disease immunotherapies
Scientific Reports (2015)
-
S-Nitrosylation in Alzheimer's disease
Molecular Neurobiology (2015)
-
Interpreting Alzheimer’s disease clinical trials in light of the effects on amyloid-β
Alzheimer's Research & Therapy (2014)