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(Mis)treating the pharmacogenetic incidentalome

Abstract

Genome-wide screening is anticipated to accelerate the development of personalized medicine by identifying and exploiting new associations between genomic variants and drug responses. However, this goal could be undermined if care is not taken to minimize the impact of pharmacogenomic associations that turn out to have narrower implications than suggested by initial studies.

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Correspondence to Isaac S. Kohane.

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Kohane, I. (Mis)treating the pharmacogenetic incidentalome. Nat Rev Drug Discov 11, 89–90 (2012). https://doi.org/10.1038/nrd3659

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