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Brentuximab vedotin


In August 2011 brentuximab vedotin (Adcetris; Seattle Genetics), a CD30-specific antibody–drug conjugate, was approved by the US Food and Drug Administration (FDA) for the treatment of patients with Hodgkin's lymphoma and patients with systemic anaplastic large cell lymphoma (ALCL).

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Correspondence to Anas Younes, Uma Yasothan or Peter Kirkpatrick.

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Competing interests

Anas Younas has received research support and/or honoraria from Seattle Genetics, Sanofi-Aventis, Novartis, Genentech, Plexxikon, Celgene, Gilead and Merck.

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Younes, A., Yasothan, U. & Kirkpatrick, P. Brentuximab vedotin. Nat Rev Drug Discov 11, 19–20 (2012).

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