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Is open innovation the way forward for big pharma?


The current, fully integrated business model of large pharmaceutical companies is increasingly considered to be unsustainable, and so new approaches that engage large and small companies, governments and academic institutions are needed. Could 'open innovation' models that have proved successful in other sectors be fruitfully adopted by the pharmaceutical industry?

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  1. Chesborough, H. W. Open Innovation: the New Imperative for Creating and Profiting from Technology 1–272 (Harvard Business School, Boston, Masschusetts, 2003).

    Google Scholar 

  2. Tapscott, D. & Williams, A. D. Wikinomics: How Mass Collaboration Changes Everything 1–320 (Portfolio, New York, 2006).

    Google Scholar 

  3. Munos, B. Can open-source R&D reinvigorate drug research? Nature Rev. Drug Discov. 5, 723–729 (2006).

    Article  CAS  Google Scholar 

  4. Huston, L. & Sakkab, N. Connect and Develop: Inside Procter & Gamble's new model for innovation. Harv. Bus. Rev. 84, 58–66 (2006).

    Google Scholar 

  5. Barnes, M. R. et al. Lowering industry firewalls: pre-competitive informatics initiatives in drug discovery. Nature Rev. Drug Discov. 8, 701–708 (2009).

    Article  CAS  Google Scholar 

  6. Hughes, B. Harnessing open innovation. Nature Rev. Drug Discov. 8, 344–345 (2009).

    Article  Google Scholar 

  7. Alexy, O. et al. Does IP strategy have to cripple open innovation?' MIT Sloane Management Rev. 51, 73–77 (2009).

    Google Scholar 

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Correspondence to Jackie Hunter.

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Hunter, J., Stephens, S. Is open innovation the way forward for big pharma?. Nat Rev Drug Discov 9, 87–88 (2010).

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