Figure 1 : Success rates from first-in-man to registration.

From: Can the pharmaceutical industry reduce attrition rates?

Figure 1

The overall clinical success rate is 11%. However, if the analysis is carried out by therapeutic areas, big differences emerge. The data are from the ten biggest drug companies during 1991–2000. (The companies are AstraZeneca, Bristol-Myers Squibb, Eli Lilly, F. Hoffman-LaRoche, GlaxoWellcome, Johnson & Johnson, Novartis, Pfizer, Pharmacia, Schering-Plough and SmithKline Beecham; data were obtained by Datamonitor in the Pharmaceutical Benchmarking Study). CNS, central nervous system.