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A call for a global ‘bigger’ data approach to Alzheimer disease

Clinical trials for Alzheimer disease drugs have an exceptionally high failure rate, discouraging investment in the field despite the unmet medical need. Drug developers need to more effectively harness existing and emerging data and digital technologies to improve the likelihood of success.

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Correspondence to Eric Perakslis.

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AETIONOMY: https://www.aetionomy.eu/en/vision.html

CancerLinQ: https://cancerlinq.org/

EPAD: http://ep-ad.org/

Pragmatic Trials of Managing Multimorbidity in Alzheimer’s Disease: https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-18-028.html

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Perakslis, E., Riordan, H., Friedhoff, L. et al. A call for a global ‘bigger’ data approach to Alzheimer disease. Nat Rev Drug Discov 18, 319–320 (2019). https://doi.org/10.1038/nrd.2018.86

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