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Impact of the Innovative Medicines Initiative on vaccine development

Nature Reviews Drug Discovery | Download Citation

Since its launch a decade ago, the European Innovative Medicines Initiative (IMI), a leading public–private partnership in life sciences, has catalysed scientific breakthroughs and the development of strategies to address complex challenges in various biomedical fields. Here, we discuss the progress of IMI projects related to vaccine research and development.

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The authors are grateful to L. Cochard (SCINNOV) for helpful discussions, and E. Oe and U. Krause (both GSK) for scientific writing services and publication management, respectively.

Author information


  1. GSK, Rixensart, Belgium.

    • Philippe Denoel
  2. Sanofi Pasteur, Marcy-l'Étoile, France.

    • Patricia Londoño-Hayes
  3. European Federation of Pharmaceutical Industries and Associations (EFPIA), Brussels, Belgium.

    • Magda Chlebus
  4. Vaccines Europe/EFPIA, Brussels, Belgium.

    • Magdalena Rodriguez de Azero


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Competing interests

The authors declare the following conflicts: P.D. is an employee of the GSK group of companies. P.L.H. is an employee of Sanofi Pasteur. M.C. and M.R.A. are employees of the European Federation of Pharmaceutical Industries and Associations (EFPIA). Functions of the authors in IMI: P.D. is the chair of the Vaccines Europe R&D Working Group, a member of the Infections Control Strategic Governing Group and a member of the BioVacSafe and PERISCOPE projects. P.L.H. is a member of the Vaccines Europe R&D Working Group, a member of the Immunology Strategic Governing Group for Vaccines Europe, leader of the FLUCOP project, EFPIA co-leader of the PERISCOPE project and oversees the IMI Portfolio on Vaccines at Sanofi Pasteur. M.C. is coordinating EFPIA input into IMI strategy development and idea/project generation and is a deputy member of the IMI Governing Board. M.R.A. is coordinating the Vaccines Europe members input to vaccine projects generation.

Corresponding author

Correspondence to Philippe Denoel.

Supplementary information

PDF files

  1. 1.

    Supplementary Figure

    Timeline of IMI vaccine consortia

  2. 2.

    Supplementary Table

    Objectives and key achievements of representative IMI vaccine projects

  3. 3.

    Supplementary Box

    Overview of IMI vaccine project budgets

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