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NIH Centers for Accelerated Innovations Program: principles, practices, successes and challenges

Nature Reviews Drug Discovery volume 16, pages 663–664 (2017)Cite this article

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Commercializing innovations in academic environments is notoriously challenging. Here, we describe the progress of the NIH Centers for Accelerated Innovations program — initiated in 2013 to address these challenges — which we believe could help set a new standard for the early-stage commercialization of biomedical innovations in academic environments.

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Acknowledgements

This work was supported in part by NIH grants U54HL119145 (B-BIC), U54HL119810 (NCAI-CC), and U54HL119893(UC-CAI) and the NHLBI's NIH Centers for Accelerated Innovations program. The authors also wish to thank R. Cannistraro for expert technical support.

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Authors and Affiliations

  1. Brigham and Women's Hospital, 75 Francis Street, Boston, 02115, Massachuchetts, USA

    Elliott M. Antman & Joseph Loscalzo

  2. Cleveland Clinic, 9500 Euclid Avenue, Cleveland, 44195, Ohio, USA

    Paul E. Di Corleto & D. Geoffrey Vince

  3. Massachusetts General Hospital, 55 Fruit Street, Boston, 02114, Massachuchetts, USA

    Mason W. Freeman

  4. Department of Medicine, David Geffen School of Medicine, UCLA, 10833 Le Conte Avenue, Los Angeles, 90095, California, USA

    Tomas Ganz & Michael Palazzolo

  5. Harvard Medical School, 250 Longwood Avenue, Boston, 02115, Massachuchetts, USA

    David E. Golan

  6. Partners Innovation, 215 First Street, Cambridge, 02142, Massachuchetts, USA

    Roger Kitterman, Erin McKenna & Lesley Watts

  7. GCIC, 10000 Cedar Avenue, Cleveland, 44106, Ohio, USA

    Mark Low

  8. RTI International, 3040 E. Cornwallis Road, Research Triangle Park, 27709, North Carolina, USA

    Alan C. O'Connor

  9. CIMIT, 125 Nashua Street, Boston, 02114, Massachuchetts, USA

    John Parrish

  10. Lerner Research Institute, 9500 Euclid Avenue, Cleveland, 44195, Ohio, USA

    Ofer Reizes

  11. Department of Medicine and Anesthesiology, UCSD School of Medicine, San Diego, 92037, California, USA

    Robert S. Ross

  12. 300 Fenway, Boston, 02115, Massachuchetts, USA

    Cheryl Vaughan

Authors
  1. Elliott M. Antman
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  2. Paul E. Di Corleto
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  3. Mason W. Freeman
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  4. Tomas Ganz
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  5. David E. Golan
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  6. Roger Kitterman
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  7. Joseph Loscalzo
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  8. Mark Low
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  9. Erin McKenna
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  10. Alan C. O'Connor
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  11. Michael Palazzolo
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  12. John Parrish
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  13. Ofer Reizes
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  14. Robert S. Ross
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  15. Cheryl Vaughan
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  16. D. Geoffrey Vince
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  17. Lesley Watts
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Consortia

for the NIH Centers for Accelerated Innovations

Corresponding author

Correspondence to Joseph Loscalzo.

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Competing interests

The authors declare no competing financial interests.

Supplementary information

Supplementary Information Table S1

Member institutions (PDF 122 kb)

Supplementary Information Table S2

NCAI approaches for soliciting potential proposals (PDF 96 kb)

Supplementary Information Table S3

NCAI program application success rates by stage and center (PDF 106 kb)

Supplementary Information Table S4

Start-up companies* (PDF 109 kb)

Supplementary Information Table S5

Technologies licensed or optioned (PDF 101 kb)

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Antman, E., Di Corleto, P., Freeman, M. et al. NIH Centers for Accelerated Innovations Program: principles, practices, successes and challenges. Nat Rev Drug Discov 16, 663–664 (2017). https://doi.org/10.1038/nrd.2017.131

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