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Paring down the placebo response

Pivotal trials of Alkermes's antidepressant ALKS 5461 show how a patented clinical trial design might be able to help control problematic placebo responses.

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Figure 1: Basic SPCD design.
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Mullard, A. Paring down the placebo response. Nat Rev Drug Discov 15, 807–808 (2016). https://doi.org/10.1038/nrd.2016.255

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