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Acknowledgements
The authors are grateful to M. Berntgen for his support in this project and would also like to thank O. Collignon for advice on the statistical methodology.
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Butlen-Ducuing, F., Pétavy, F., Guizzaro, L. et al. Challenges in drug development for central nervous system disorders: a European Medicines Agency perspective. Nat Rev Drug Discov 15, 813–814 (2016). https://doi.org/10.1038/nrd.2016.237
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DOI: https://doi.org/10.1038/nrd.2016.237
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