Accelerating global innovation to address antibacterial resistance: introducing CARB-X

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Abstract

A global response to the chronic shortfall in antibiotic innovation is urgently needed to combat antimicrobial resistance. Here, we introduce CARB-X, a new global public–private partnership that will invest more than US$350 million in the next 5 years to accelerate the progression of a diverse portfolio of innovative antibacterial products into clinical trials.

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References

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    Review on Antimicrobial Resistance. Tackling drug-resistant infections globally: final report and recommendations http://amr-review.org (2016).

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    Laxminarayan, R. et al. Antibiotic resistance—the need for global solutions. Lancet Infect. Dis. 13, 1057–1098 (2013).

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    Outterson, K. New business models for sustainable antibiotics. Chatham House http://www.chathamhouse.org/publications/papers/view/197446 (2014).

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Author information

Correspondence to Kevin Outterson.

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Competing interests

J.H.R. is an employee and shareholder of AstraZeneca Pharmaceuticals, non-executive board member, senior advisor and shareholder of F2G Pharmaceuticals; non-executive board member of Adenium Biotech ApS; Expert-in-residence, Wellcome Trust; and operating partner and consultant, Advent Life Sciences. P.J. is executive director of AMR Centre Ltd; non-executive director of Redx Pharma Plc; non-executive director of Yprotech Ltd; non-executive director of Biovictrix Therapeutics Ltd; and owner and director of Intelia Consulting.

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CARB-X

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Outterson, K., Rex, J., Jinks, T. et al. Accelerating global innovation to address antibacterial resistance: introducing CARB-X. Nat Rev Drug Discov 15, 589–590 (2016) doi:10.1038/nrd.2016.155

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