Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Breast cancer

Why do women opt for contralateral prophylactic mastectomy?

The decision of patients with breast cancer to have contralateral mastectomies is often related to their genetic risk. However, the increasing frequency of this surgical approach is also associated with social and psychological issues such as celebrity experiences and fear of contralateral breast cancer. Appropriate counselling may better inform patients' surgical choices.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Pesce, C. E. et al. Changing surgical trends in young patients with early stage breast cancer, 2003 to 2010: a report from the national cancer data base. J. Am. Coll. Surg. 219, 19–28 (2014).

    Article  Google Scholar 

  2. Hawley, S. T., et al. Social and clinical determinants of contralateral prophylactic mastectomy. JAMA Surg. 149, 582–589 (2014).

    Article  Google Scholar 

  3. Yi, M. et al. Factors affecting the decision of breast cancer patients to undergo contralateral prophylactic mastectomy. Cancer Prev. Res. (Phila.) 3, 1026–1034 (2010).

    Article  Google Scholar 

  4. Brewster, A. M. & Parker, P. A. Current knowledge on contralateral prophylactic mastectomy among women with sporadic breast cancer. Oncologist 16, 935–941 (2011).

    Article  Google Scholar 

  5. Lostumbo, L., Carbine, N., Wallace, J. & Ezzo, J. Prophylactic mastectomy for the prevention of breast cancer. Cochrane Database Syst. Rev. 4, Art. No.: CD002748 (2004). http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD002748.pub2/abstract.

  6. Finch, A. P. et al. Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation. J. Clin. Oncol. 32, 1547–1553 (2014).

    Article  Google Scholar 

  7. Preventive mastectomy. Wikipedia.org [online], (2014).

  8. Crerand, C. E., Infield, A. L. & Sarwer, D. B. Psychological considerations in cosmetic breast augmentation. Plast. Surg. Nurs. 27, 146–154 (2007).

    Article  Google Scholar 

  9. Kling, R. E. et al. The scope of plastic surgery according to 2434 allopathic medical students in the United States. Plast. Reconstr. Surg. 133, 947–956 (2014).

    CAS  PubMed  Google Scholar 

  10. Borzekowski, D., Guan, Y., Smith, K. C., Erby, L. H. & Roter, D. L. The Angelina effect: immediate reach, grasp, and impact of going public. Genet. Med. http://dx.doi.org/10.1038/gim.2013.181 (2013).

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Aron Goldhirsch.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Goldhirsch, A., Gelber, S. Why do women opt for contralateral prophylactic mastectomy?. Nat Rev Clin Oncol 11, 443–444 (2014). https://doi.org/10.1038/nrclinonc.2014.116

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrclinonc.2014.116

This article is cited by

Search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer