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Antithrombotic therapy in 2017

Advances in atherosclerosis, atrial fibrillation, and valvular disease

Nature Reviews Cardiology volume 15, pages 71–72 (2018)Cite this article

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In 2017, several high-impact studies in thrombosis were published. Refinements were made in the optimal therapy for patients with stable atherosclerosis or with atrial fibrillation undergoing percutaneous coronary intervention. Risk scores to determine duration of antiplatelet therapy were developed. The potential risk of subclinical valve leaflet thrombosis was identified.

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Figure 1: Antiplatelet and anticoagulant pathways.

References

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Authors and Affiliations

  1. Deepak L. Bhatt is at the Brigham and Women's Hospital Heart & Vascular Center, Harvard Medical School, 75 Francis Street, Boston, Massachusetts 02115, USA.,

    Deepak L. Bhatt

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  1. Deepak L. Bhatt
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Correspondence to Deepak L. Bhatt.

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Competing interests

D.L.B. declares the following relationships. Advisory Board: Cardax, Elsevier Practice Update Cardiology, Medscape Cardiology, Regado Biosciences. Board of Directors: Boston VA Research Institute, Society of Cardiovascular Patient Care. Chair: American Heart Association Quality Oversight Committee. Data Monitoring Committees: Cleveland Clinic, Duke Clinical Research Institute, Harvard Clinical Research Institute (PORTICO DSMB), Mayo Clinic, Mount Sinai School of Medicine, Population Health Research Institute. Honoraria: American College of Cardiology (Senior Associate Editor, Clinical Trials and News, ACC.org), Belvoir Publications (Editor in Chief, Harvard Heart Letter), Duke Clinical Research Institute (clinical trial steering committees), Harvard Clinical Research Institute (RE-DUAL executive committee), HMP Communications (Editor in Chief, Journal of Invasive Cardiology), Journal of the American College of Cardiology (Guest Editor; Associate Editor), Population Health Research Institute (COMPASS steering committee, operations committee, publications committee, and US national co-leader), Slack Publications (Chief Medical Editor, Cardiology Today's Intervention), Society of Cardiovascular Patient Care (Secretary/Treasurer), WebMD (CME steering committees). Other: Clinical Cardiology (Deputy Editor), NCDR-ACTION Registry Steering Committee (Chair), VA CART Research and Publications Committee (Chair). Research Funding: Amarin, Amgen, AstraZeneca, Bristol-Myers Squibb, Chiesi, Eisai, Ethicon, Forest Laboratories, Ironwood, Ischemix, Lilly, Medtronic, Pfizer, Roche, Sanofi Aventis, The Medicines Company. Royalties: Elsevier (Editor, Cardiovascular Intervention: A Companion to Braunwald's Heart Disease). Site Co-Investigator: Biotronik, Boston Scientific, St. Jude Medical (now Abbott). Trustee: American College of Cardiology. Unfunded Research: FlowCo, Merck, PLx Pharma, Takeda.

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Bhatt, D. Advances in atherosclerosis, atrial fibrillation, and valvular disease. Nat Rev Cardiol 15, 71–72 (2018). https://doi.org/10.1038/nrcardio.2017.212

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